imbecilitate
To weaken, as to the body or the mind; to enfeeble.
obsolete, transitive
The man, being skilful in natural magick, did use all the artifices his subtilty could devise to imbecilitate the earl.
Where it comes from
From imbecility + -ate (verb-forming suffix); compare -itate and Medieval Latin imbēcillitō.
Adapted from the Wiktionary entry imbecilitate (CC BY-SA 4.0).