grame
To vex; grill; make angry or sorry.
obsolete, transitive
For when they have take the sea, / At Sandwich, or at Winchelsea, / At Bristol, or where that it may be, / Their hearts begin to fail.
Men may leave all games, / That sailën to St James; / For many a man it grames / When they begin to sail.To grieve; to be sorry; to fret; to be vexed or displeased.
intransitive, obsolete
The crane and the curlewe thereat gan to grame.
Where it comes from
From Middle English gramen, gramien, from Old English gramian, gremian (“to anger, enrage”), from Proto-Germanic *gramjaną (“to grill, vex, irritate, grieve”), from Proto-Indo-European *gʰrem- (“to rub, grind, scrape”). Cognate with German grämen (“to grieve”), Danish græmme (“to grieve”), Swedish gräma (“to grieve, mortify, vex”).
Adapted from the Wiktionary entry grame (CC BY-SA 4.0).